A material made up of two or more elements in chemical combination represents a

A material made up of two or more elements in chemical combination is referred to as a compound. Compounds are substances formed when two or more elements are chemically bonded together in a specific ratio. This results in a new substance with properties that are distinct from those of the individual elements that comprise it.

In chemistry, the formation of a compound involves a chemical reaction, where the atoms of the elements rearrange to achieve a stable electron configuration. For example, water (H₂O) is a compound formed from hydrogen and oxygen atoms chemically bonded in a 2:1 ratio.

On the other hand, a chemical change refers to a process where the chemical composition of a substance is altered, often resulting in the formation of new products. A physical change involves changes in physical properties but not in chemical composition, such as changes in state (like freezing or boiling). Lastly, a mixture refers to a combination of two or more substances that do not chemically react and can often be separated by physical methods. In the case of a compound, however, the elements are interconnected at a molecular level and cannot be separated by physical means. Thus, the best representation of a material made up of two or more elements in chemical combination is indeed a compound.